Endocrine Abstracts

Glycogen storage disease type 1 is a rare autosomal recessive disorder. Osteoporosis is one of the long term complications. However factors associated with low bone mass has not fully understood. Metabolic derangements that occur with poor control may contribute to bone disease. Low bone mass could be caused by hypogonadtropic hypogonadism, a unique issue identified in GSD. Herein we report a patient with GSD type 1, osteoporosis and hypogonadotropic hypogonadism. A 20 years o...

Background: Hypophysitis is a rare group of disease characterized with infla mmation of the pituitary gland. Rarity of the disease obviates development of a treatment strategy. We aimed to present the nationwide data of the demographics, clinical and radiological characteristics, treatment modalities and responses of the patients diagnosed with hypophysitis in a retrospective manner.Methods: The endocrinology clinics all over the country were invited to ...

Glycogen storage disease (GSD) type 1 is an autosomal recessive disorder in which there is problem in glucose 6 phosphatase system. Glucose-6-phosphate transport protein deficiency is found in GSD type 1b. There is disorder in glucose metabolism, lack of glucose production in liver. Hypoglycemia, seizures, lactic acidosis, hyperuricemia and hyperlipidemia are some of the components. Affected people may also have short stature, pancytopenia and inflammatory bowel disease. Our a...

Introduction: Radioiodine ablation with a whole-body scan is a well known therapeutic regimen for differentiated thyroid cancer. I-131 uptake in the breast has been described with a variety of normal and pathologic conditions such as gynecomastia, supernumerary breasts, fibroadenoma and lactational duct cyst or galactocele. Here we report a case with an incidental radioiodine uptake in breast who turned out to be breast cancer.Case report: A 70 years old...

Background: Pregnancy and lactation-related osteoporosis can be associated with fractures during the last trimester or early postpartum period. During lactation, a 3–10% bone loss in the lumbar vertebrae has been detected within 3–6 months. When lactation is reduced bone mineral density(BMD) values reach early postpartum levels within 6–18 months. Certain comorbidities, such as hypercalciuria, premature ovarian failure, low body mass index, oligoamenorrhea, seve...

Background: Although most solid primary tumors can metastasize to the adrenal glands, lung cancer is the most common, followed by renal cell carcinoma, melanoma and colorectal cancer. However endometrial cancer metastasis to adrenal gland is very rare. There are only a few case in literature. Endometrial cancer is the most common gynecological malignancy. In this case, we present a case of adrenal gland metastasis of endometrial cancer.Case presentation:...

Introduction: The aim of this study is to investigate association between Hashimoto’s thyroiditis (HT) and vestibular function and the possible effect of levothyroxine (LT4) treatment on vestibular functionPatients and methods: We recruited 61 patients with HT and 30 age and gender matched healthy individuals for the study. Of 30 patients with HT were on LT4 treatment (group I) and 31 patients were treatment naive (group II). None of the patients ha...

The prevalance of incidentally discovered adrenal masses increased in last three decades. The major clinical concern is the risk of malignancy and hormone overproduction but most of them are non-fonctional and benign. Current practices in the management of adrenal incidentalomas reevaluated the follow-up suggestions considering low probability of the transformation of a benign and non-functional adrenal mass to a malignant or functional one. Therefore, in the present study we ...

Sarcoidosis is a multisystem granulomatous disease of unknown cause. The prevalence of neurosarcoidosis is about 5–15%. Hypothalamo-pituitary sarcoidosis is even rarer (<1% of cases evaluated for sellar and stalk lesions).Case Report: A 33-year-old man presented to urology department with erectile dysfunction which started six months ago. Hormonal evaluation revealed gonadotropin deficiency and hyperprolactinemia (Total testosterone: 30.5 ng/dl,...

Introduction: The risk of malignancy has often been reported to be more frequent in Graves’ disease (GD) than non-autoimmune thyroid nodules. However, frequency of thyroid nodules, diagnostic yield of fine-needle aspiration (FNA), and their potential for bearing malignancy in GD are still debatable issues. We aimed to determine the prevalence, ultrasonographic and cytological features, and the rate of malignancy outcome of thyroid nodules in a group of patients with GD.</...